National Research Center for Women & Families
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What You Need to Know About the Flu

By Susan Dudley, PhD and Cecily Dvorak, MD
October 2007

News about the flu is everywhere. It can be frightening and often confusing. Here are the facts.

Human flu--or influenza--is caused by a virus, usually striking in temperate climates like the United States between October and May. There is also concern about a dangerous new strain that could potentially reach pandemic proportions. How is seasonal flu related to avian flu, and what do we need to know to protect our families?

The specific type of virus that causes the flu is different every year, which is why we need to get annual flu shots instead of a one-time vaccination. Antibiotics don't work on the flu, because antibiotics kill bacteria, not viruses. Public health experts keep close watch on the flu viruses moving through animal populations to predict which ones are likely to spread to people and how likely they are to spread. From that information, new vaccines are developed each year that will work against the particular viral strain that is expected. Vaccine production takes at least six months.

The life cycle of all flu begins in birds. Some birds (wild ducks, for example) can serve as "hosts" for the virus. This means that they can spread it to other birds or farm animals without getting sick themselves. These viruses rarely pose a health risk to humans. But if they mutate into forms that can also infect people, the annual human flu cycle begins.

Scientists have identified at least 144 strains of flu virus. For the past 20 years, viruses from two main "families" have predominated as the cause of annual human flu outbreaks. What makes the "avian flu" different from the seasonal flu that we are already familiar with is that it comes from a virus family that has not been known to infect humans before. This means that no one has developed any natural immunity based on previous exposures. In addition, this form of the virus causes more severe responses in the human body, than what we normally expect from the flu, so the mortality from this virus could be much higher.

Here is a side-by-side comparison of the seasonal flu and the avian (bird) flu.

 

Seasonal Flu

H5N1 "Avian" Flu

How it spreads
Droplets from an infected person's nose or mouth get into a healthy person’s nose, mouth, or eyes.
  How it spreads
Fewer than 200 people worldwide are known to have been infected with the H5N1 avian flu up to now. Most appear to have gotten the virus through direct exposure to infected birds, and there is little evidence that the virus has developed the capacity to spread directly from person to person. Unless or until it does, it poses little danger to humans.
     
Symptoms
Flu symptoms are often similar to, but more severe than, a "common cold." They include coughing, sore throat, and fever. Most people recover in 1-2 weeks, but some develop pneumonia or other very serious complications requiring hospitalization.
  Symptoms
Because this virus has not yet mutated to a form that can easily spread in human populations, it is not clear what symptoms it will cause if that happens. Scientists predict that it could be quite severe, producing high rates of life-threatening complications, especially affecting the lungs.
     
The bad news
With annual variations in types of flu, about 36,000 Americans die and more than 200,000 are hospitalized for flu-related complications every year. Most Americans don't get flu shots.
  The bad news
As many as 35-50% of the people infected with the H5N1 virus since 1997 have died. In contrast, the "Spanish flu" epidemic of 1918, from which an estimated 50 million people died worldwide, had a much lower death rate.
     
The good news
Because most annual flu viruses are related to previous viruses, people tend to build "partial immunities" to the viruses that spread each year. That means their immune systems will be able to figure out how to resist new flu infections more quickly than if it were something drastically different from what they've been exposed to before.

  The good news
Scientific and public health communities all around the world are on alert to pick up the first signs if the H5N1 virus becomes a serious threat to humans. Efforts are underway to develop new anti-viral medications and vaccines in case it begins spreading among humans.

     

What you should do

  • Get a flu shot every year.
  • Wash your hands often.
  • Cover your mouth and nose when you sneeze or cough.
  • Keep your immune system strong through exercise, healthy food, and plenty of sleep.

    Although you can be contagious with flu before your symptoms develop, stay home when you're sick to avoid spreading it to even more people.

 

What you should do

  • Don't panic! Your family is NOT in imminent danger from this strain of flu.
  • Follow the news and stay alert for public health advisories.
  • Continue to follow all recommendations for avoiding seasonal flu.
     

What else?
Influenza infects about 20% of the population each year. It is the sixth-leading cause of death in the United States, so all flu should be taken seriously. An annual flu shot is the best weapon against catching and spreading flu.

Avian flu is not a new disease. It is simply a new form of seasonal influenza. And while it is important for us to have a good understanding of the potential threats, it is also important to keep this information in perspective. Flu pandemics have occurred ten times in the last 300 years--most recently in 1918-19, 1957-58 and 1968-69. Their seriousness depends on many factors. So far, however, the H5N1 strain does not possess the characteristics necessary to produce worldwide human-to-human infection, and there is no reason for people to panic or to make special efforts to obtain personal supplies of antiviral medications. Information is our best ally in efforts to contain and minimize an influenza pandemic.

This article will be updated regularly.

Last update:   09 January 2006.

 

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