Irritable Bowel Syndrome Medication: Update on Zelnorm

Irritable bowel syndrome (IBS) is an uncomfortable intestinal problem that affects nearly one in five Americans, most of whom are women. Unfortunately, known treatments only help with IBS symptoms, not the cause. More so, these treatments often have dangerous side effects. How is it that these drugs are still on the market if they are unsafe? The answer is because of a drug development process known as “treatment IND” (Investigational New Drug). The most recent of these treatment INDs involves a medication known as Zelnorm. What are the dangers, and should you take it for your IBS?

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NCHR Testimony at the FDA about New Spine Device, Barricaid Anular Closure

December 12, 2017, Patients who suffer with back pain need better alternatives for long term relief. The Barricaid device might be the answer, but the limited data provided suggests it is unlikely to offer the kinds of benefits that patients need. The study indicates substantial device failures. Its use in limited discectomy remains unknown, because most subjects had more extensive surgeries. In addition, the short-term benefits appear to be modest and wane after 24 months. Long term studies with blinding conducted inside the US may provide more certainty, but at this time the data are insufficient to recommend approval.

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